Muhammad Shaybani

Muhammad Shaybani captured Samarkand from the Timurid ruler Babur. This conquest marked the end of Timurid rule in Transoxiana and established the Shaybanid dynasty, making Samarkand the capital of the Uzbek Khanate.

Muhammad Shaybani besieged and captured Bukhara from the Timurids. This conquest added another major Silk Road city to his domain, strengthening Uzbek control over Central Asian trade routes.

Muhammad Shaybani launched a campaign against the Kazakh Khanate, defeating them near the Syr Darya. This victory secured the northern borders of the Uzbek Khanate and prevented Kazakh incursions into Transoxiana.

Muhammad Shaybani was defeated and killed by the Safavid Shah Ismail I at the Battle of Marv. His death ended the Shaybanid expansion into Khorasan and led to the temporary Safavid occupation of Uzbek territories.