Ptolemy V Epiphanes

Ptolemy V lost the province of Coele-Syria to the Seleucid king Antiochus III after the Battle of Panium. This defeat marked the end of Ptolemaic control over the region and significantly reduced the kingdom's territory and influence.

The Rosetta Stone was inscribed with a decree from the Council of Priests at Memphis, praising Ptolemy V. The text was written in hieroglyphic, demotic, and Greek scripts, later enabling the decipherment of Egyptian hieroglyphs by Jean-Fran

Ptolemy V married Cleopatra I, daughter of Antiochus III, as part of a peace treaty ending the Fifth Syrian War. The marriage temporarily stabilized relations between the Ptolemaic and Seleucid kingdoms, but Cleopatra later acted as regent for their son.

Ptolemy V's forces finally crushed the native Egyptian revolt that had begun under Ptolemy IV. The rebel leader Ankhmakis was captured and executed, restoring Ptolemaic control over Upper Egypt but at the cost of further alienating the Egyptian population.