
Founded Bogota and conquered the Muisca.
Quesada led an expedition of 800 men from the Caribbean coast into the Colombian interior. He defeated the Muisca Confederation, a loose alliance of Chibcha-speaking chiefdoms, through a combination of military force and diplomacy. The conquest took 2 years.
Quesada founded the city of Santa Fe de Bogot
Quesada was appointed Adelantado (governor) of the New Kingdom of Granada by the Spanish Crown. He held this position until his death, overseeing the administration and expansion of the colony. He also served as a judge in the Royal Audiencia.
Quesada led an expedition into the eastern plains of Colombia (Llanos Orientales) in search of El Dorado. The expedition was a disaster, with most of the 300 men dying from disease, starvation, and attacks by indigenous peoples. Quesada returned to Bogot
Quesada died of leprosy in Mariquita, Colombia, on February 16, 1579. He was buried in the Cathedral of Bogot